The placebo consisted of the same adjuvant
OK now it appears in three documents. This being the third one. I find that hard to believe, but you can do a search yourself with Google, Google Scholar, Google News, and Google blog search, and discover this for yourself.
(edit) Google already found this entry! It even lists it on the web search. (/edit)
It appears here, www.blackwell-synergy.com/
and here, broken link-> http://linkinghub.elsevier.com/IHUB_downtime02.htm
One is a broken link, the other wants 39 US dollars to read it. Considering the volume and page numbers have question marks, I think I will try an alternative method of finding the article.
www.blackwell-synergy.com/doi/pdf/10.1111/j.1525-1438.2007.01123.x
International Journal of Gynecological CancerVol. 0 Issue 0 Page ???
Safety and immunogenicity of a vaccine targeting human papillomavirus types 6, 11, 16 and 18: a randomized, placebo-controlled trial in 176 Korean subjects
S. KANG, K.H. KIM, Y.T. KIM, Y.T. KIM, J.H. KIM, Y.S. SONG, S.H. SHIN, H.S. RYU, J.W. HAN, J.H. KANG, S.Y. PARK
It doesn't really matter, the issue isn't with the article at all. It is with the entire methodology of how they "tested" the Gardasil vaccine. During the clinical trials, they didn't use a placebo, they used amorphous aluminum hydroxyphosphate sulfate as the placebo.
Here is the abstract for the trial.
http://www.ncbi.nlm.nih.gov/pubmed/17986242
We performed a randomized, double-blind, placebo-controlled study in 176 volunteers aged 9-23 years. Using a 2:1 ratio for randomization, 117 women were assigned to quadrivalent HPV (20 mug type 6, 40 mug type 11, 40 mug type 16, and 20 mug type 18) vaccine and 59 women to placebo. Individuals received vaccine at day 1, month 2, and month 6 and provided blood samples for analysis at enrollment at month 7. Analyses were done as specified in the study protocol. Quadrivalent HPV vaccine was generally well tolerated, with no vaccine-related serious adverse experiences. Quadrivalent HPV vaccine induced seroconversion for each vaccine-related HPV type. At month 7, vaccine-induced type-specific antibody titer was high. In conclusion, administration of quadrivalent HPV VLP vaccine to Korean women aged 9-23 years was generally well tolerated and highly immunogenic.
Note the bolded parts of the abstract. Just like all the other abstracts about Gardasil and clinical trials, they don't tell you the truth. They didn't use a Placebo, they used amorphous aluminum hydroxyphosphate sulfate dissolved in saline solution.
I am not making this up. So when they claim there were no adverse effects, they are comparing the vaccine to a big slug of aluminum injected into muscle tissue. Let me repeat that.
So when they claim there were no adverse effects, they are comparing the vaccine to a big slug of aluminum injected into muscle tissue.
You might think that is more than a bit deceptive. Because it is. In fact, it is a huge deception. It makes the entire clinical trial an example of bad science, bad medicine, and it is the opposite of Evidence Based Science.
How could the FDA approve that? How can anyone who is a scientist look at that and not see it?
This could be an entire series. This is unbelievable. As a scientific, rational person, I am deeply disturbed by this.
Which brings us back to that phrase, "The placebo consisted of the same adjuvant". Redefining placebo isn't just against the rules, it is against the very basis of science, medicine and evidence based science.
12 comments:
How is 225 µg of amorphous aluminum hydroxyphosphate sulfate considered "a big slug of aluminum"? The LD50 is 4640mg/kg. Let's do the math, shall we?
225 ug = 0.225 mg
For those of you still trying to follow along.... the amount considered a "Big slug of aluminum" is less than 1/4 of a mg. it takes 3,000 mg to make you slightly ill and almost 5,000 mg is the dose required to kill half the members of a tested population after a specified test duration.
Watch out for claims of "Evidenced based". Do your own research. Dig for your answers of who, what, when, where, why, how and how much. People say and twist what they want to in order to fill their own agendas.
When testing something, the placebo effect is ruled out by using a placebo. This is to be able to dismiss symptoms and side effects that have nothing to do with the material being injected.
If the placebo is not an inert substance, or worse, it consists of material being tested, it is useless as a placebo.
The phrase "big slug" was hyperbole.
It was amorphous aluminium hydroxyphosphate sulphate, not aluminium. It was 1,950ug of aahs a novel ingredient that has never undergone safety assessment, nor approved for use in medicines.
Your logic is akin to saying that cyanide is only carbon and nitrogen which are both safe ingredients.
@ SFX The amorphous aluminum hydroxyphosphate sulfate was not the substance being tested. The HPV proteins in the vaccine are what was being tested. So, in this case, the placebo is still a placebo. It is far more concerning that this site would seek to locate a clinical trial that no one else can find whilst completely disregarding the mountains and mountains of evidence-based trials in the US and other countries, but I guess it doesn't fit the narrative huh.
First the aluminum crosses the blood brain barrier. Second the the evidence for aluminum deposits in Alzheimer's patient is well documented. Zero amount of aluminum is safe in the body.
The Package Insert for Gardasil States the placebo is amorphous aluminum hydroxyphosphate sulfate. I agree with the above statement: if you want to find out if the compound being injected is safe, proper research methods are to use an inert substance. This if particularly important for vaccines in which the adjuvants can be more harmful than the other compounds in a vaccine. https://www.fda.gov/downloads/biologicsbloodvaccines/vaccines/approvedproducts/ucm111263.pdf
†
"AAHS Control = Amorphous Aluminum Hydroxyphosphate Sulfate"
Ready the study. Saline placebo was also used in addition to the AAHS.
Regarding ld50 are you referring to orally administed aluminum or injected? It is my understanding that only about 1/4 of 1% of orally administered aluminum is bio available. That’s a 400 fold difference.
The LD50 is for ingested aluminum which is roughly 0.3% bioavailable. Injected aluminum is 100% bioavailable. Some research shows that a significant amount of injected aluminum eventually makes it to the brain. It's also been linked to autoimmune disease.
About 2.3% of the Gardasil test subjects in the AAHS placebo group developed an autoimmune disease within six months. About 2.6% of the Gardasil group developed autoimmune disease within six months.
But there was a third placebo group in the Gardasil trials that is not very well known. The third placebo group received either the carrier solution or saline. That group developed no autoimmune disease within six months. The third group is briefly mentioned in the prescribing information, but in the tables showing adverse events the placebo group is listed as saline placebo group + adjuvant placebo group.
Also, the actual Gardasil vaccine on the market has twice the aluminum of the Gardasil vaccine used in the clinical trials.
Wow. Sometimes the comments are more informative than my research.
Wow, to think of what was unfolding when I made that post... here we are arguing over them redefining placebo, unaware that about a year later they would redefine vaccine, and Fauci would prove everyone wrong (at one point or another) by taking every possible position in every possible argument, and even make some novel arguments no one ever even considered... Like the claim that covid19 and future pandemics were caused because we're "out of balance with nature" because of modern agricultural methods...
Anyway, I hope the pandemic hasn't been to rough on you S F X.
I'm good
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